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• Catalyzes the formation of a phosphodiester bond between juxtaposed 5'-phosphate and 3'-hydroxyl termini in duplex DNA or RNA • Catalyse la ligation de 2 fragments d'ADN double brin à bouts francs • Covalently joins DNA fragments with complementary cohesive ends • Seals single-stranded nicks in duplex DNA, RNA or DNA/RNA hybrids • Suitable for cloning of restriction fragments and joining linkers or adapters to blunt-ended DNA • Available in 20000 and 100000 unit formats* • *Cohesive End Unit - 200 CEU = 3 Weiss units